Probiotics and necrotizing enterocolitis.

Probiotics for the prevention of necrotizing enterocolitis.

Necrotizing enterocolitis (NEC) remains a significant cause of morbidity and mortality for low birth weight premature infants. Prematurity, ischemia, formula feeding, and bacterial colonization are risk factors for the self-perpetuating cycle of damaged intestinal epithelia, inflammation, bacterial entry, sepsis, and shock that characterizes NEC. Probiotics are food supplements containing live ...

Probiotics: Possible Strategies to Prevent Necrotizing Enterocolitis in Neonates

Probiotics and Synbiotics in Necrotizing Enterocolitis: Where Are We?

Preterm neonates are susceptible to complications, including necrotizing enterocolitis, a leading cause of morbidity and mortality. Probiotics are live microorganisms, that when administered in adequate amounts, confer a health benefit to the host. Current evidence suggests that probiotics are effective in decreasing the incidence of NEC in preterm infants. Nondigestible oligosaccharides ‘prebi...

Effectiveness of probiotics in the prophylaxis of necrotizing enterocolitis in preterm neonates: a systematic review and meta-analysis.

OBJECTIVE To elucidate the benefits of using probiotics in the prevention of necrotizing enterocolitis (NEC) and its complications in preterm newborns. METHOD This was a systematic review of randomized controlled trials, which included studies retrieved from three databases (MEDLINE, Embase, and LILACS), using a combination of the terms (necrotizing enterocolitis) AND (probiotics). RESULTS ...

Effects of Probiotics on the Reduction in Incidence of Necrotizing Enterocolitis in Premature (< 37 Weeks Gestation) Neonates